Pulsed Electrical Stimulation in Patients with Osteoarthritis of the Knee: Follow Up in 288 Patients Who Had Failed Non-Operative Therapy

Publication:

Surgical Technology International XV - Orthopaedic Surgery

Article title:

Author(s)

Jack Farr, M.D.
Associate Clinical Professor, Orthopedic Surgery
Orthopaedics Indianapolis
Indiana University Medical Center
Indianapolis, Indiana, USA

Michael A. Mont, M.D.
Director, Joint Preservation & Reconstruction
Rubin Institute for Advanced Orthopedics
Baltimore, Maryland

Douglas Garland, M.D.
Clinical Professor of Orthopedics
University of Southern California
Memorial Orthopaedic Surgical Group
Long Beach, California

Jacques R. Caldwell, M.D.
Medical Consultant
Bionicare Medical Technologies, Inc.
Sparks, Maryland

Thomas M. Zizic, M.D.
Associate Professor
Department of Medicine

Johns Hopkins University School of Medicine
Baltimore, Maryland
President & CEO
Bionicare Medical Technologies, Inc.
Sparks, Maryland

Abstract

Background: Optimized pulsed electrical stimulation (PES) regulates chondrocyte genes, enhances production of cartilage matrix materials, and inhibits production of matrix catabolic factors.
Methods: This prospective, cohort study examined the use of a PES device in treatment of knee osteoarthritis (OA) in patients who had failed non-operative therapy. Primary outcome measures were patient and physician global evaluation, and patient assessment of knee pain.

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